Manchester United captain Roy Keane has cracked two ribs and will be out of action for three weeks, the Premier League club said on Wednesday.
The 25-year-old, who joined PSV from Partizan Belgrade in 2000, was top scorer with 31 goals in the Dutch first division last season.
Barcelona earned a valuable 2-1 away win at Chelsea, with the home side playing most of the match with only 10 men.
Chelsea's players thought the referee erred in sending off Asier del Horno
Manchester City clinched a 1-0 victory at Tottenham Hotspur, while Chelsea were held to a 0-0 draw at home by Aston Villa.
Police in riot gear struggled to contain West Ham fans at the end of the third round match at Stamford Bridge, which Chelsea won 1-0.
The Chelsea striker could be sidelined for up to six weeks with a calf injury, according to manager Claudio Ranieri.
Manager Gerard Houllier could sign a goalkeeper on a short-term deal with Chris Kirkland and Jerzy Dudek both sidelined through injury.
West Ham United and Chelsea both narrowly avoided ignominious FA Cup exits with narrow wins against lower-league opposition but Everton marked Frank Lampard's first game in charge by sauntering past Brentford into the fifth round on Saturday.
The 1-0 victory gave Chelsea top slot in the premier league, ahead of Arsenal.
Chelsea coach Claudio Ranieri said his team's positive approach held the secret to their spectacular 4-0 Champions League away win over Lazio.
Argentina striker Hernan Crespo, who spent last season on loan at AC Milan, is to resume his career at Chelsea
A place in the Istanbul final on May 25 beckons if Chelsea and Milan can exploit home advantage.
"I have to be honest with myself so I have to appeal," he told a news conference on Friday, a day after calling the punishment "an absolute disgrace".
Chelsea beat Bayern Munich 4-2 while while Milan beat city rivals Inter 2-0 in the UEFA Champions League first leg quarter-finals.\n\n
Chelsea stretched their lead at the top of the Premier League to 11 points with a 1-0 win over struggling West Bromwich Albion at Stamford Bridge on Tuesday.
Making the most of a rare start for Sarri's side, Loftus-Cheek inspired Chelsea to a 3-1 Europa League win over the Belarus champions at Stamford Bridge on Thursday.
Rediff.com gives you a glimpse of the best sporting action from the week gone by.
Chelsea clinched their first Premier League title for five years with a 1-0 victory against Crystal Palace at a jubilant Stamford Bridge on Sunday.
Champions Arsenal eased to a comfortable 2-0 home win over Middlesbrough on Saturday, extending their lead at the top of the English premier league to two points.
Tottenham Hotspur bolstered their hopes for a top-four finish and extended Chelsea's miserable run
Chelsea, Manchester City and Manchester United enjoyed comfortable wins in the English Premier League on Saturday as fans returned to stadiums after an eight-month absence.
Czech Republic goalkeeper Petr Cech ended a highly successful 11-year spell at English champions Chelsea when he moved to Premier League rivals Arsenal on Monday.
Both managers were fined by the FA but only Tuchel will serve a ban as he was found "largely culpable" for the fracas following the managers' post-match handshake.
The Manchester United captain believes the club needs a new striker to partner Dutchman Ruud van Nistelrooy upfront.
